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Practice question answers HIV infection

Practice question answers HIV infection © Jun Wang, MD, PhD   1. A. This patient presents with flu-like symptoms and diarrhea. While these presentations are not specific, the history of sexual activity with multiple partners should indicate the need of HIV screening . The recommended initial screening test for HIV is a combined immunoassay for HIV p24 and HIV antibodies. HIV-1/2 antibody test is performed after positive reaction in the initial screening test of p24 and HIV antibodies, for confirmation. HIV RNA test is usually performed when initial screening test is negative, but early HIV infection is strongly suspected, due to window period of HIV infection. Monospot test is commonly used for diagnosis of infectious mononucleosis . Rapid plasma reagin test is a screening test for primary and secondary syphilis .   2. C. See discussion of question 1.   3. A. Early HIV infection refer to the first few months, usually 6 months of HIV infection. Patien...

Practice questions HIV infection

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Practice questions HIV infection  © Jun Wang, MD, PhD   1. Use this case for next seven questions . A 24-year-old man presents to the clinic with a 5-day history of fever, sore throat, myalgias, diarrhea and diffuse maculopapular rash on his trunk. He returned 2 months ago from an international trip where he ate food from street vendors and engaged in unprotected sexual intercourse with a few partners. His past medical history is positive for type 1 diabetes. He has a 10 pack-year history of cigarette smoking, drinks 3 beers every day, and has been using marijuana for the last 2 years. Physical examination reveals generalized lymphadenopathy and a faint nonpruritic rash on the chest. Rapid tests from flu and COVID are negative. Which of the following is the most appropriate next step in diagnosis? A. HIV p24 and antibody test B. HIV-1/2 antibody differentiation immunoassay C. HIV RNA PCR test D. Monospot test E. Rapid plasma reagin 2. A 24-year-old man presents to t...