Neoplasms of bone

Bone tumors 

Updated: 08/12/2022

© Jun Wang, MD, PhD


General
  • Most common type of bone tumors: Metastatic malignancies
  • Majority of primary bone tumors are benign
Diagnostic considerations
  • History: Age, bone involved, site of bone involved
  • Radiological studies for invasive features
  • Morphology/immunohistochemistry
Features suggestive of malignancy
  • Radiology: Invasion, bone destruction
  • Microscopic: Pleomorphism, necrosis, invasive growth
Classifications
  • Hematopoietic:
Myeloma
Lymphoma
  • Bone forming
Osteoid osteoma
Osteoblastoma
Osteosarcoma
  • Cartilage forming
Osteochondroma
Chondroma
Chondrosarcoma
Chondroblastoma
Chondromyxoid fibroma
  • Unknown origin
Giant cell tumor
Aneurysmal bone cyst
Ewing sarcoma
Adamantinoma
Tumor like lesions of bone and joint
Practice questions


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