Practice Question Answers Anemia VII
Practice Question Answers Anemia VII © Jun Wang, MD, PhD Abbreviations: Hb: hemoglobin HCT: hematocrit MCV: Mean Corpuscular Volume MCH: Mean Corpuscular Hemoglobin RDW: Red Cell Distribution Width TIBC: total iron binding capacity 1. A. This patient has a few conditions that may cause fatigue. However, dark urine and jaundice are commonly seen with hemolysis . Her low hemoglobin and elevated reticulocyte count and bilirubin are consistent with hemolytic anemia . Positive DAT is consistent with immune hemolytic anemia . Depression, hypothyroidism, liver disease and Prozac seldom cause hemolysis . 2. E. The peripheral blood smear reveals many spherocytes (RBCs without central pallor area). Warm auto-immune antibodies cause spherocytic changes in immune hemolytic anemia . Cold agglutinin disease is characterized by recurrent painful episodes of fingers and toes and bluish discoloration inv...