Practice question answers II lymphoid
Practice questions answers Lymphoid neoplasms II © Jun Wang, MD, PhD 07/26/2018 1. D. Young adults present with cervical lymphadenopathy is highly suspicious for Hodgkin lymphoma . The microscopic features and immunohistochemistry profiles are typical for a classical Hodgkin lymphoma , nodular sclerosis type. Anaplastic large-cell lymphoma has markedly atypical tumor cells with horseshoe or donut-shape large cells that are positive for ALK and CD30. Diffuse large B cell lymphoma is positive for CD20. Follicular lymphoma is positive for CD10 and CD20, but negative for CD15 and CD30. Both follicular lymphoma and reactive lymphadenopathy do not have Reed-Sternber cells. 2. A. Hodgkin lymphoma is associated with EBV. HHV8 is associated with primary effuse lymphoma and Kaposi sarcoma. HIV post a risk factor for various lymphomas, but most likely would not be directly associated with Hodgkin lymphoma . HPV is associated with carcinomas, especially squamous cell carci