Pathology Notes

Practice questions V answers, female genital tract Pathology of placenta © Jun Wang, MD, PhD 1. A. This patient has clinical presentations of acute inflammation. With the physical examination finding of purulent vaginal discharge, and the opaque discolored fetal membrane, this is most likely acute chorioamnionitis . Eclampsia has hypertension, proteinuria, edematous changes and neurological abnormalities such as seizures and coma. Preeclampsia has hypertension, proteinuria, edematous changes without neurological abnormalities such as seizures and coma. Placenta accreta is implantation into myometrium, and is not commonly associated with acute inflammation. Succenturiate placenta is additional placental lobe, usually asymptomatic, although posting a risk for hemorrhage and thromboembolism.   2. C. The characteristic feature of acute chorioamnionitis is neutrophilic infiltration of amnion or chorionic villi. Neutrophilic infiltration of umbilical cord is seen in acute fun

Practice questions V, female genital tract Pathology of placenta © Jun Wang, MD, PhD 1. Use this case for the next two questions. A 21-year-old G4P0A3 woman at gestation 35 weeks presents with painless vaginal fluid leaking for 3 hours. She has a history of cervical herpes 4 years ago but no abnormality is noted through current prenatal examinations. She denies any history of alcohol or cigarette usage. Physical examination reveals a cervical dilation of 2 cm. Laboratory tests are within normal range. Group B strep prophylaxis was initiated but the patient declined induction. A week later she experiences contraction. Physical examination reveals a temperature of 39.5 degree Celsius and copious foul smelling yellow greenish vaginal discharge. Laboratory tests reveals a leukocytosis with left shift. Since fetal monitoring indicates tachycardia and late decelerations, a cesarean section for delivery was performed. The male neonatal has an Apgar score of 3 and 9 at a and 5 min.