Pathology Notes

Practice questions III answers, female genital tract     Pathology of Ovary A © Jun Wang, MD, PhD 1. B. A single ovarian cyst lined by benign follicular cells is a follicular cyst . Endometrioid cyst (endometrioma, chocolate cyst) is ovarian endometriosis , typical has benign endometrial glands and stroma, as well as hemorrhagic changes. Luteal cyst is lined by luteinized granulosa cells and theca cells with abundant eosinophilic granular cytoplasm and small round to oval nuclei. Mucinous cystadenoma is usually multilocular with thick fluid contents, and lined by columnar benign mucinous cells. Serous cystadenoma is commonly unilocular with thin clear fluid and lined by single layer of flat to cuboidal cells with cilia. 2. C. Ovarian cyst in young woman, lined by benign cells with abundant eosinophilic granular cytoplasm and small round to oval nuclei, and central hemorrhagic changes is likely a luteal cyst . Mucinous cystadenocarcinoma has markedly atypical cells with mu

Practice questions III, female genital tract Pathology of ovary A © Jun Wang, MD, PhD 1. A 43-year-old woman presents with vague left lower abdomen discomfort for 3 days. She does not have fever, weight loss, vaginal bleeding or discharge. She has a history of cervical condyloma and chlamydial urethritis 10 years ago. Her past medical history is otherwise unremarkable. She has multiple family members in her maternal side diagnosed with breast, ovarian and endometrial carcinoma. Pelvic sonographic examination reveals a 5 cm cystic mass at her left ovary. An excisional biopsy was performed and the lesion is a unilocular cyst with smooth lining. Microscopically it has a fibrous wall covered by multiple layers of loosely cohesive cells with moderate amount of cytoplasm and small round dark nuclei. What is the diagnosis? A. Endometrial cyst B. Follicular cyst C. Luteal cyst D. Mucinous cystadenoma E. Serous cystadenoma 2. A 28-year-old woman pres