Hemophilia arthropathy

Hemophilia arthropathy
Updated: 07/25/2023
© Jun Wang, MD, PhD

General features
  • Permanent joint disease due to repeated haemarthrosis
Clinical presentations
  • Usually large joints
  • Either monoarticular or oligoarticular
  • Pain
  •  Dysfunction
Key pathogenesis
  • Reactive proliferation and regeneration of chronically inflamed synovium, due to repeated hemorrhagic damage
Key morphological features
  • Synovial hyperplasia, chronic inflammation
  • Fibrosis
  • Cartilage erosion
  • Subarticular cysts



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