Peripheral T-Cell Lymphoma, Unspecified

Peripheral T-Cell Lymphoma, Unspecified
Updated: 08/24/2020
© Jun Wang, MD, PhD

General features
  • Heterogeneous group
  • Mature T cell neoplasms
  • Most common nodal T cell lymphoma
  • Highly aggressive
  • Usually high stage with skin and lung involvement
Clinical presentations
  • Nodal or extranodal
Key morphological features
Markers
  • Frequently loss of T-cell markers, such as CD5, CD7
Genetic abnormalities
  • Clonal T-cell receptor rearrangement



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Lymphoid neoplasms