Dermatofibroma

Dermatofibroma
Updated: 07/28/2020
© Jun Wang, MD, PhD

General features
  • AKA benign fibrous histiocytoma (superficial), dermal fibrous histiocytoma, sclerosing hemangioma, histiocytoma cutis
  • Part of WHO classification for skin tumors, not soft tissue tumors
  • Very common benign, slowly growing tumor
  • More common in women
Clinical presentations
Pathogenesis
  • Clonal proliferation of stromal cells, most likely fibroblasts
  • Fibrosis liked associated with TGF-beta
Key morphological features
Markers
Treatment
  • Excision

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Contents

Pathology notes Jun Wang, MD, PhD 1. General information Frequently discussed syndromes Terms of dermatology Terms of hematology 2. Primary immunodeficiency disorders 3. Hemodynamic abnormalities Shock Thrombosis and embolism Bleeding disorders 4.  Benign blood cell disorders Anemia Benign white cell disorders 5. Hematopoietic neoplasms Lymphoid neoplasms Myeloid neoplasms Histiocytic neoplasms: Langerhans cell histiocytosis 6. Cardiovascular system Pulmonary hypertension Cardiovascular system tumors 7. Respiratory tract tumors 8. Gastrointestinal tract Congenital disorders Infectious gastroenteritis Oral cavity Esophagus Stomach Intestinal tumors Salivary glands Exocrine pancreas and gallbladder 9. Urinary system Kidney masses Lower urinary tract 10. Male reproductive system 11. Female genital tract 12. Breast 13. Endocrine organs Pituitary gland Adrenal gland Thyroid gland Parathyroid gland Endocrine pancreas...
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Anemia

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Lymphoid neoplasms

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