Embryonoal rhabdomyosarcoma

Embryonoal rhabdomyosarcoma 

Updated: 08/18/2021

© Jun Wang, MD, PhD

General features
  • Most common rhabdomyosarcoma subtype
  • Usually children ages 3-10 years
  • Commonly in nasal and oral cavities, orbit, middle ear, prostate, paratesticular region
  • Better prognosis if botryoid type
Clinical presentations
  • Painless mass
  • Most common location: head and neck paratesticular region
Key morphological features
Markers
  • Positive for myogenin, desmin, myoD1
Genetic abnormalities
  • PAX3
Botryoid variant
Treatment
  • Surgery
  • Radiation
  • Chemotherapy


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