Leiomyoma

Leiomyoma 

Updated: 08/07/2020

© Jun Wang, MD, PhD

General features
  • Benign tumor of smooth muscle
  • Commonly in uterus, skin, subcutis, deep soft tissue and GI
  • If multiple: Leiomyomata
Clinical presentations
  • Mass
  • Uterine leiomyoma may cause dysfunctional uterine bleeding or lower abdomen pressure-related symptoms
Key morphological features
Markers
  • Positive for desmin, smooth muscle actin
Genetic abnormalities
  • HMGIC, HMGIY, MED12 for uterine leiomyoma
Treatment
  • Excision


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Contents

Pathology notes Jun Wang, MD, PhD 1. General information Frequently discussed syndromes Terms of dermatology Terms of hematology 2. Primary immunodeficiency disorders 3. Hemodynamic abnormalities Shock Thrombosis and embolism Bleeding disorders 4.  Benign blood cell disorders Anemia Benign white cell disorders 5. Hematopoietic neoplasms Lymphoid neoplasms Myeloid neoplasms Histiocytic neoplasms: Langerhans cell histiocytosis 6. Cardiovascular system Pulmonary hypertension Cardiovascular system tumors 7. Respiratory tract tumors 8. Gastrointestinal tract Congenital disorders Infectious gastroenteritis Oral cavity Esophagus Stomach Intestinal tumors Salivary glands Exocrine pancreas and gallbladder 9. Urinary system Kidney masses Lower urinary tract 10. Male reproductive system 11. Female genital tract 12. Breast 13. Endocrine organs Pituitary gland Adrenal gland Thyroid gland Parathyroid gland Endocrine pancreas...
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