Lipoma

Lipoma
Updated: 08/07/2020
© Jun Wang, MD, PhD

General features
  • Most common soft tissue tumor
  • Benign
Clinical presentations
  • Single or multiple
  • Soft mass
Key morphological features
Treatment
  • Excision



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Contents

Pathology notes Jun Wang, MD, PhD 1. General information Frequently discussed syndromes Terms of dermatology Terms of hematology 2. Immunodeficiency disorders HIV infection   Primary immunodeficiency disorders 3. Hemodynamic abnormalities Shock Thrombosis and embolism Bleeding disorders Blood transfusion 4.  Benign blood cell disorders Anemia Benign white cell disorders 5. Hematopoietic neoplasms Lymphoid neoplasms Myeloid neoplasms Histiocytic neoplasms: Langerhans cell histiocytosis 6. Cardiovascular system Pulmonary hypertension Cardiovascular system tumors 7. Respiratory tract tumors 8. Gastrointestinal tract Congenital disorders Infectious gastroenteritis Oral cavity Esophagus Stomach Intestinal tumors Salivary glands Exocrine pancreas and gallbladder 9. Urinary system Kidney masses Lower urinary tract 10. Male reproductive system 11. Female genital tract 12. Breast 13. Endocrine organs Pituitary gland Ad...
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Anemia

Anemia Updated: 07/13/2024 © Jun Wang, MD, PhD   General features Decrease in red cell mass Hemoglobin: Levels of hemoglobin in a specific volume of whole blood Hematocrit: Fraction of whole blood composed of red blood cells Red cell count: Quantity of red cell in a specific volume of whole blood Three major groups based on RBC sizes Microcytic Normocytic Macrocytic Three major causes Blood loss: acute or chronic Increased red cell destruction: hemolysis Reduced production: marrow failure due to genetic abnormality or nutritional deficiency Etiology Genetic abnormality Hemoglobinopathies RBC cytoskeletal abomorlities Enzyme abnormalities Fanconi anemia Nutritional deficiencies: iron, VB12, folate, general malnutrition Physical etiologies: trauma, burns, frostbite, prosthetic valves, etc Chronic diseases: chronic infections, neoplasia, autoimmune disorders, kidney or liver diseases, etc Infectious diseases: hepatitis, sepsis , malaria, e...
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Bleeding disorders

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Bleeding disorders   Updated: 07/25/2025 © Jun Wang, MD, PhD Hemostasis Primary: Vasoconstriction, platelet activation Secondary: Coagulation cascades Results: Blood clot formation Activation of platelets Coagulation system Intrinsic pathway: XII, XI, IX, VIII (8-12 except 10) Extrinsic pathway: VII Common pathway: X, V, prothrombin (II), fibrinogen (I) (4 smallest US dollar bills) Etiology of bleeding disorders Vascular dysfunction, including vitamin C deficiency, telangiectasia, allergic purpura, purpura associated with infections such as meningococcus and Rocky Mountain spotted fever, etc Platelet disorders Thrombocytopenia Thrombocytosis Platelet dysfunctions associated with uremia, MDS , medications (NSAIDs etc) Bernard-Soulier syndrome, etc  Coagulopathy Von Willebrand disease Hemophilia A Hemophilia B Acquired hemophilia Liver disease associated coagulopathy Vitamin K deficiency, including warfarin associated coagulopathy Other anticoagulan...
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