Undifferentiated pleomorphic sarcoma

Undifferentiated pleomorphic sarcoma
Updated: 08/07/2020
© Jun Wang, MD, PhD

General features
  • High grade undifferentiated sarcoma
  • Older term “Malignant Fibrous Histiocytoma” NOT proper anymore
  • Usually age 50+ years, slightly more common in male
  • Diagnosis of exclusion
Clinical presentations
  • Deep seated mass with progressive enlargement
  • More common in lower extremities
Key morphological features
Markers
  • Variable, usually inconclusive
Treatment
  • Excision
  • Radiation
  • Chemotherapy


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Contents

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