Medullary Sponge Kidney

Medullary Sponge Kidney 

Updated: 09/30/2021

© Jun Wang, MD, PhD

General features
  • Sporadic
  • Rarely progress to end stage renal disease due to complications (infections, nephrolithiasis)
  • May be associated with hemihypertrophy of body, Marfan’s, Caroli’s and Ehlers-Danlos syndrome
Etiology and pathophysiology
  • Likely developmental abnormality
Clinical features
  • Usually asymptomatic with normal renal function
  • Commonly incidental finding by image studies
  • Adult onset of calcifications, stones, hematuria and infection
  • May have hypercalcemia
Pathological findings
Diagnosis
  • Intravenous pyelography or CT: Renal tubular ectasia
Differential diagnosis



Management
  • Treatment of stones
  • Treatment of flank pain
  • Monitor renal function


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