Cardiac myxoma

Cardiac myxoma 

Updated: 10/22/2020

© Jun Wang, MD, PhD

General features
  • Most common primary heart tumor
  • Sporadic (majority) or familial (Carney syndrome)
  • 90% occur in atria, 80% on left side
  • More common in women
  • Mean age 50 years
Clinical presentations
  • Most commonly in left atrium, followed by right atrium (Typically in fossa ovalis)
  • Myxoma triad:
Intracardiac flow obstruction: left-side heart failure or syncope, etc
Embolic phenomena
Constitutional symptoms: weight loss, fever, etd
Key morphological features
Diagnosis
  • Imaging studies: Transthoracic echocardiography (TTE), transesophageal echocardiography (TEE)
  • If familial, may screening family members, molecular tests for PRKAR1A mutation
Treatment
  • Excision
Prognosis


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