Clear cell carcinoma
Clear cell carcinoma
Updated: 12/16/2020
© Jun Wang, MD, PhD
General features
- A type 2 (estrogen independent) endometrial carcinoma
- Post-menopausal
- Highly aggressive
Pathogenesis
- Less defined
Clinical presentations
- Asymptomatic or uterine bleeding
Pathological findings
- Clear or hobnail cells
- Marked cytological atypia
Molecular abnormality
- p53
- Her2
- E-cadherin
Treatment
- Surgery
- Chemotherapy
- Radiation therapy
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