Phyllodes tumor
Phyllodes tumor
Updated:07/01/2023
© Jun Wang,
MD, PhD
General features
- Biphasic tumor with hypercellular stroma
- Three categories based on histology: benign, borderline and malignant
- Malignant type more common in older women
- Local recurrence common if not completely removed
- Malignant type may metastasize to lung, bone, CNS
- 1q+ most common chromosomal abnormality
Clinical presentations
- Firm mass
Key morphological features
- Leaf like processes
- Hypercellular stroma
- Variable hemorrhage, necrosis
Treatment
- Excision
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