Sclerosing adenosis

Sclerosing adenosis
Updated: 12/10/2018
© Jun Wang, MD, PhD

General features
  • Glandular and stromal proliferation
  • Mean age 30 years
  • Slightly increased risk for invasive carcinoma
Clinical presentations
  • Recurring pain that tends to be linked to the menstrual cycle
  • Mammogram abnormalities
Key morphological features
  • Increased number of distorted/compressed small glands
  • Background stromal proliferation/fibrosis
  • NO cytological atypia
  • Intact myoepithelial cell layer (marked by positive reactivity to CD10, actin, p63)
Treatment
  • Usually no treatment needed
  • Follow up



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