Subacute thyroiditis

Subacute lymphocytic thyroiditis 

Updated: 01/25/2023

© Jun Wang, MD, PhD

General features
  • Transient, painless hyperthyroidism
  • Relatively uncommon, usually women
  • Unknown etiology
  • Spontaneously resolves
Key laboratory findings
  • Elevated T3 and T4, low radioactive iodine uptake
Pathological features
  • Diffuse goiter or slightly enlarged thyroid gland
  • Preserved lobular pattern
  • Follicular destruction
  • Variable lymphocytic infiltrate
  • Rare/no oncocytic change, rare/no focal fibrosis
Treatment
  • Usually do not need treatment
  • Beta block if hyperthyroidism



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