Gastroschisis

Gastroschisis
Updated: 02/22/2019
© Jun Wang, MD, PhD

General features
  • Congenital midline abdominal wall defect
  • May be associated with smoking, agriculture chemicals
Pathogenesis
  • Four hypotheses
  • Failure of mesoderm to form in the body wall
  • Herniation of bowel due to amnion rupture around umbilical ring
  • Weakening of the body wall and gut herniation due to abnormal involution of right umbilical vein
  • Body wall damage and gut herniation due to yolk sac artery disorder
Clinical presentations
  • Full thickness paraumbilical abdominal wall defect
  • Exposed internal organs without membrane covering
Prenatal diagnosis
  • Image studies
Treatment
  • Surgical repair

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