Gastroschisis

Gastroschisis
Updated: 02/22/2019
© Jun Wang, MD, PhD

General features
  • Congenital midline abdominal wall defect
  • May be associated with smoking, agriculture chemicals
Pathogenesis
  • Four hypotheses
  • Failure of mesoderm to form in the body wall
  • Herniation of bowel due to amnion rupture around umbilical ring
  • Weakening of the body wall and gut herniation due to abnormal involution of right umbilical vein
  • Body wall damage and gut herniation due to yolk sac artery disorder
Clinical presentations
  • Full thickness paraumbilical abdominal wall defect
  • Exposed internal organs without membrane covering
Prenatal diagnosis
  • Image studies
Treatment
  • Surgical repair

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Contents

Pathology notes Jun Wang, MD, PhD 1. General information Frequently discussed syndromes Terms of dermatology Terms of hematology 2. Primary immunodeficiency disorders 3. Hemodynamic abnormalities Shock Thrombosis and embolism Bleeding disorders 4.  Benign blood cell disorders Anemia Benign white cell disorders 5. Hematopoietic neoplasms Lymphoid neoplasms Myeloid neoplasms Histiocytic neoplasms: Langerhans cell histiocytosis 6. Cardiovascular system Pulmonary hypertension Cardiovascular system tumors 7. Respiratory tract tumors 8. Gastrointestinal tract Congenital disorders Infectious gastroenteritis Oral cavity Esophagus Stomach Intestinal tumors Salivary glands Exocrine pancreas and gallbladder 9. Urinary system Kidney masses Lower urinary tract 10. Male reproductive system 11. Female genital tract 12. Breast 13. Endocrine organs Pituitary gland Adrenal gland Thyroid gland Parathyroid gland Endocrine pancreas M
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Anemia

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Lymphoid neoplasms

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