Acanthosis nigricans

Acanthosis nigricans
Updated: 01/31/2020
© Jun Wang, MD, PhD

General features
  • Increased pigmentation of skin
  • Usually in patients > 40
  • May be associated with endocrine diseases, congenital disorders and visceral malignancies, especially GI
  • May occur as inherited disorder
  • Most are "benign" type, either autosomal dominant or associated with resistance to insulin, including diabetes, obesity and Cushing's disease
Clinical features
Pathological features
Management
  • Focus on underlying disorders


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