Merkel cell carcinoma of skin

Merkel cell carcinoma of skin 

Updated: 03/17/2021

© Jun Wang, MD, PhD

General features
  • Uncommon
  • Aggressive neuroendocrine tumor
  • Origin and etiology unclear
  • Commonly in the head and neck, elderly and light skin population
  • May be associated with Merkel cell polyomavirus, UV, radiation, and immunosuppresion
  • Tendency to recur and metastasize
  • Distant metastasis nearly fatal
Clinical features
Key pathological features
Markers
Management
  • Excision
  • Radiation
  • Chemotherapy



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