Pilomatricoma

Pilomatricoma
Updated: 03/28/2019
© Jun Wang, MD, PhD

General features
  • AKA pilomatrixoma, calcified epithelioma of Malherbe
  • Most benign 
  • Arising from hair matrix
  • Usually children and young adults in head, neck or upper extremities
  • Likely associated with CTNNB (beta-catenin) mutation or bcl-2 overexpression
  • Aggressive pilomatrixoma: Atypical histology, locally invasive with local recurrence
  • Malignant pilomatrixoma: Cytologic atypia, infiltrative border, transition to squamous cells, necrosis, local recurrence and metastasize
Clinical features
Pathological features
Management
  • Excision



Back to skin tumors
Back to contents

Comments

Popular posts from this blog

Contents

Anemia

Lymphoid neoplasms