Rosacea
Rosacea
Updated: 12/21/2023
© Jun Wang, MD, PhD
General features
- AKA acne rosacea
- May involve skin or eye
- More common in light skin populations, adult
- Five subtypes
- Erythematotelangiectatic
- Granulomatous
- Papulopustular
- Phymatous
- Ocular
- Usually clinical diagnosis
Pathogenesis
- Unclear etiology, likely multi-factorial
- Immune dysfunction
- Ultraviolet radiation
- Physical or chemical trauma
- Microorganisms: Demodex mites (D. folliculorum and D. brevis), bacillus oleronius
- Vascular hyper-reactivity
- Probably genetic background: family history
Clinical features
- May involve skin and eyes
- Skin manifestions
- Central facial erythema
- Papules, pustules, flushing, telangiectasia
- Phymatous changes (rhinophyma)
- Ocular manifestions
- Lid margin telangiectases
- Interpalpebral conjunctive injection
- Spade-shaped corneal infiltrate
Pathological findings
- Perifollicular lymphocytic infiltration and vascular ectasia
Management
- Avoid triggering factors
- Laser, surgery, etc
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