Carcinoid of lungs

Well-differentiated neuroendocrine tumor of lung 

Updated: 10/15/2020

© Jun Wang, MD, PhD

General features
  • Well-differentiated neuroendocrine neoplasm
  • Locally invasive, rarely metastasizes
  • more common in female, age <60
  • May have MEN1 mutation
  • NOT related to smoking
Key clinical features
  • May be asymptomatic
  • Symptoms of bronchial obstruction
  • Presentations associated with hormone production
Key morphological features
Markers
  • Positive: Cytokeratin
  • Positive for neuroendocrine markers: CD56, neuron specific enolase, chromogranin, synaptophysin
  • Negative: CD45 and other lymphocytic markers
Treatment
  • Excision


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Contents

Pathology notes Jun Wang, MD, PhD 1. General information Frequently discussed syndromes Terms of dermatology Terms of hematology 2. Primary immunodeficiency disorders 3. Hemodynamic abnormalities Shock Thrombosis and embolism Bleeding disorders 4.  Benign blood cell disorders Anemia Benign white cell disorders 5. Hematopoietic neoplasms Lymphoid neoplasms Myeloid neoplasms Histiocytic neoplasms: Langerhans cell histiocytosis 6. Cardiovascular system Pulmonary hypertension Cardiovascular system tumors 7. Respiratory tract tumors 8. Gastrointestinal tract Congenital disorders Infectious gastroenteritis Oral cavity Esophagus Stomach Intestinal tumors Salivary glands Exocrine pancreas and gallbladder 9. Urinary system Kidney masses Lower urinary tract 10. Male reproductive system 11. Female genital tract 12. Breast 13. Endocrine organs Pituitary gland Adrenal gland Thyroid gland Parathyroid gland Endocrine pancreas M
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Anemia

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Lymphoid neoplasms

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