Teratoma

Teratoma
Updated: 12/07/2018
© Jun Wang, MD, PhD

General feature
  • Mature, immature or monodermal
Mature teratoma
  • Only contains mature/adult tissues
  • Usually teenage women (solid) or children (cystic)
  • May rupture into peritoneal cavity
  • Excellent prognosis, even with peritoneal implants
  • Dermoid cyst: Mature teratoma which resembles skin
  • Pathological features
Solid or cystic
May contain greasy material composed of keratin, hair and teeth
Mature tissue, most commonly skin and glial tissue
Immature teratoma
  • Prepubertal or young women (mean 18 years)
  • Have immature components, usually neurogenic and mesodermal
  • Considered malignant
  • Recurrence commonly in 2 years
  • Treatment: Surgery, chemotherapy
Struma ovarii
  • Rare
  • Monodermal teratoma
  • Predominantly of mature thyroid tissue
  • May have thyrotoxicosis or malignancies (usually papillary thyroid carcinoma)
  • If malignant, may harbor BRAF mutation


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