Teratoma
Teratoma
Updated: 12/07/2018
© Jun Wang, MD, PhD
General feature
- Mature, immature or monodermal
Mature teratoma
- Only contains mature/adult tissues
- Usually teenage women (solid) or children (cystic)
- May rupture into peritoneal cavity
- Excellent prognosis, even with peritoneal implants
- Dermoid cyst: Mature teratoma which resembles skin
- Pathological features
Solid or cystic
May contain greasy material composed of
keratin, hair and teeth
Mature tissue, most commonly skin and glial
tissue
Immature teratoma
- Prepubertal or young women (mean 18 years)
- Have immature components, usually neurogenic and mesodermal
- Considered malignant
- Recurrence commonly in 2 years
- Treatment: Surgery, chemotherapy
Struma ovarii
- Rare
- Monodermal teratoma
- Predominantly of mature thyroid tissue
- May have thyrotoxicosis or malignancies (usually papillary thyroid carcinoma)
- If malignant, may harbor BRAF mutation
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