Thecoma

Thecoma
Updated: 12/08/2018
© Jun Wang, MD, PhD

General features
  • Usually > 40 years old, 65% after menopause
  • May be hormonally active, associated with estrogenic and occasionally (if steroid cells present) androgenic symptoms
  • Usually benign
  •  Luteinized thecomas: Thecoma with features of steroid hormone secreting cells; may be associated with sclerosing peritonitis and ascites
  • Fibrothecoma: Combination of fibroma and thecoma
Clinical presentations
  • Mass
  • Presentations associated with estrogen effects: abnormal uterine bleeding
Key morphological features
  • Usually unilateral
  • Well-defined, firm, solid, yellow tumor
  • Spindle cells with moderate pale cytoplasm containing lipid droplets and central nuclei
  • Reticulin fibers surrounding individual cells (note: reticulin surrounds clusters of cells in granulosa cell tumors)
Treatment
  • Surgery


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