Thyroid carcinoma

Thyroid carcinoma
Updated: 12/13/2018
© Jun Wang, MD, PhD

General features
  • Usually excellent prognosis, except anaplastic carcinoma
  • Four major types:
Papillary carcinoma: Most common, diagnosed by nuclear features
Follicular carcinoma: Diagnosed by identifying vascular or capsular invasion
Anaplastic (undifferentiated) carcinoma: Rare, worst prognosis
Medullary carcinoma: C cell origin, produce calcitonin, familial cases associated with MEN2A or 2B syndromes
  • Express thyroglobulin except medullary type carcinoma (express calcitonin)
Genetic abnormalities
Treatment
  • Surgery
  • Radioiodine therapy
  • TSH suppressive therapy
  • Molecular therapies



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Contents

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