Glucagonoma

Glucagonoma 

Updated: 01/21/2021

© Jun Wang, MD, PhD

General features
  • Alpha cell tumor
  • Rare
  • Likely malignant
  • Produce glucagon
  • More common in adult women with large solitary tumor
  • Elevated serum glucagon
Clinical presentations
Diagnosis
  • Patients with necrolytic migratory erythema, glucose intolerance, chronic diarrhea should be suspected
  • Diagnosed based on inappropriately elevated plasma glucagon levels and image studies
Managements
  • Surgery
  • Management of glucose intolerance and diabetes



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