Insulinoma

Insulinoma 

Updated: 01/21/2021

© Jun Wang, MD, PhD

General features
  • Most common pancreatic endocrine tumor
  • Beta cell tumor
  • Usually benign and functionally active
  • More common in adults, if onset before 20, probably MEN1
Clinical presentations
  • Whipple’­s triad: Symptoms of hypoglycemia (stupor, confusion, loss of consciousness), glucose < 50 mg/dl, symptoms relieved by glucose or symptoms caused by fasting or exercise
Key Laboratory findings
  • Hypoglycemia
  • Elevated insulin
Pathological features
Managements
  • Surgery



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