Carcinoma ex pleomorphic adenoma

Carcinoma ex pleomorphic adenoma 

Updated: 02/13/2021

© Jun Wang, MD, PhD

General features
Clinical features
  • Sudden increase in growth, pain or facial paralysis, facial tingling, trismus
  • Likely recur, metastasis
Pathological features
  • Infiltrating tumor with hemorrhage or necrosis
  • Malignant components in the background of pleomorphic adenoma
  • Most common adenocarcinoma with irregular glands, atypical cells, necrosis, active mitosis, etc
Management
  • Surgery
  • Radiotherapy, chemotherapy, possibley WT1 based immunotherapy, etc
  • Prognosis depends on extent, staging, grade, etc


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Contents

Pathology notes Jun Wang, MD, PhD 1. General information Frequently discussed syndromes Terms of dermatology Terms of hematology 2. Primary immunodeficiency disorders 3. Hemodynamic abnormalities Shock Thrombosis and embolism Bleeding disorders 4.  Benign blood cell disorders Anemia Benign white cell disorders 5. Hematopoietic neoplasms Lymphoid neoplasms Myeloid neoplasms Histiocytic neoplasms: Langerhans cell histiocytosis 6. Cardiovascular system Pulmonary hypertension Cardiovascular system tumors 7. Respiratory tract tumors 8. Gastrointestinal tract Congenital disorders Infectious gastroenteritis Oral cavity Esophagus Stomach Intestinal tumors Salivary glands Exocrine pancreas and gallbladder 9. Urinary system Kidney masses Lower urinary tract 10. Male reproductive system 11. Female genital tract 12. Breast 13. Endocrine organs Pituitary gland Adrenal gland Thyroid gland Parathyroid gland Endocrine pancreas...
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Anemia

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