GU tract congenital anomalies

GU tract congenital anomalies 

Updated: 01/27/2021

© Jun Wang, MD, PhD

Ureter anomalies
  • Double and bifid ureters: Associated with duplication of renal pelvis
  • Ureteropelvic junction (UPJ) obstruction
    • Most common causes of hydronephrosis in children
    • May be associated with agenesis of contralateral kidney
  • Diverticula
    • Asymptomatic or associated with recurrent urinary tract infections
    • Outpouching identified by image studies (Intravenous pyelogram, etc)
Bladder anomalies
  • Vesicoureteral reflux: Risk for infection and reflux nephropathy
  • Diverticula: Predominantly in men; risk for infection and stone
  • Exstrophy of the bladder
    • Bladder mucosa exposed to the surface exterior
    • Defect in the anterior abdominal wall
    • Developmental failure
    • Risk for adenocarcinoma of bladder
  • Patent urachus
    • Failure of urachal canal obliteration
    • Urination through umbilicus
    • Risk for infection and adenocarcinoma
    • May be associated with urachal cysts
Penile anomalies
  • Hypospadias
    • Most common congenital abnormality of male external genitalia other than cryptorchidism
    • Urethra opens onto ventral surface of penis or scrotum
    • Failure of fusion of urethral folds
  • Epispadias
    • Urethra opens onto dorsal surface of penis
    • Maybe part of  exstrophy-epispadias complex
  • Associated with abnormal descent of testes, urinary tract malformations, obstruction, urinary tract infections and possibly infertility if orifices are near base of penis
  • Treatment: Surgery unless minor



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