Lichen sclerosus
Lichen sclerosus Updated: 01/04/2021 © Jun Wang, MD, PhD General features Mid age or older Chronic lymphocyte mediated May occur anywhere Risk factor for squamous cell carcinoma Clinical presentations Very itchy and scratchy skin Atrophic appearance Key morphological features Atrophic epidermis Loss of rete ridges Fibrotic dermis Management Topical super-potent corticosteroids Calcineurin inhibitors, tacrolimus and pimecrolimus Oral or topical retinoids Surveillance for squamous cell carcinoma Biopsy recommended to rule out squamous cell carcinoma Back to female genital tract Back to contents