Ovarian choriocarcinoma

Ovarian choriocarcinoma
Updated: 12/07/2018
© Jun Wang, MD, PhD

General features
  • Possible origins
Ovarian pregnancy (gestational choriocarcinoma)
Germ cell tumor (pure or mixed, non-gestational choriocarcinoma)
Surface epithelial tumor with choriocarcinomatous differentiation
  • More common in children and adolescents
  • Metastases common at diagnosis
Clinical presentations
  • Presentation similar to ectopic or tubal pregnancy
Key Laboratory findings
  • Elevated hCG
Key morphological features
  • Soft with hemorrhage and necrosis
  • Microscopically similar to uterine choriocarcinoma
  • Cytotrophoblast, intermediate trophopblast and multinucleated syncytiotrophoblast
Treatment
  • Surgery
  • Chemotherapy



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