Ovarian clear cell carcinoma

Ovarian clear cell carcinoma
Updated: 12/07/2018
© Jun Wang, MD, PhD

General feature
  • AKA mesonephroid adenocarcinoma
  • Associated with endometriosis or endometrioidcarcinoma of the ovary
  • Probably a variant of endometrioid carcinoma
  • Usually ages 40 - 59 years
  • Stage for stage, similar prognosis to other ovarian carcinomas
Key morphological features
  • Tubular-cystic, papillary or solid
  • Hobnail cells (nuclei that protrude into lumina)
  • Clear cytoplasm (glycogen, mucin, fat)
Treatment
  • Surgery, chemo

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