Testicle choriocarcinoma

Testicle choriocarcinoma 

Updated: 01/28/2021

© Jun Wang, MD, PhD

General features

• Most commonly a component of mixed tumor
• May present initially as metastasis to liver, lung, etc

Pathological findings

• Morphology similar to ovarian or uterine choriocarcinoma
• Hemorrhage and necrosis
• Cytotrophoblast and syncytiotrophoblast

Marker

• Elevated serum hCG
• Positive: hCG, cytokeratin, PLAP
• Negative: OCT ¾, AFP

Management

• Orchiectomy with or without retroperitoneal lymph node dissection, chemo if with metastasis

Back to testicle tumors
Back to pathology of male reproductive system
Back to contents