Ovarian germ cell tumor

Ovarian germ cell tumor
Updated: 12/07/2018
© Jun Wang, MD, PhD


General feature
  • 20 - 30% of ovarian tumors
  • Usually children and young adults
  • May have mixed components
  • Serum markers important for diagnosis and follow up
Clinical features
  • Sudden onset abdominal pain, abdominal enlargement
Markers
  • hCG: Choriocarinoma and tumors containing syncytiotrophoblasts
  • AFP: Yolk sac tumor
  • Elevated both hCG and AFP: Embryonal carcinoma, polyembryoma
Classification
Treatment
  • Surgery
  • Chemotherapy

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