Pathology of exocrine pancreas and gallbladder

Pathology of exocrine pancreas and gallbladder
Updated: 03/14/19
© Jun Wang, MD, PhD

Key anatomy and histological features
  • Head, body and tail 
  • Exocrine pancreas: Majority of pancreatic tissue, glandular epithelial cells
Predominantly at the head
Drain through pancreatic duct
Acini, ducts
  • Endocrine pancreas: Islets, pale endocrine cells
Alpha: secrete glucagon (20% 0f cells)
Beta: insulin (70% of cells)
Delta: somatostatin (5% of cells)
PP cells: pancreatic polypeptide
Non neoplastic disorders
Cystic neoplasm
Non cystic neoplasm
Gallbladder disorders


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