Osteoblastoma

Osteoblastoma
Updated: 07/27/2018
© Jun Wang, MD, PhD

General features
  • Also called giant osteoid osteoma
  • Usually > 2 cm
  • Slightly more common in female, mean age 20 years old
Most common sites:
  • Spine and sacrum
Clinical presentations
  • Pain, worse at night, NOT relieved by NSAIDs
Key pathogenesis
  • Progress pain, NOT respond to aspirin
Key radiological findings
  • Radiolucent nidus
  • Surrounding bony sclerosis and cortical thickening
  • No invasion
Key morphological features
  • Anastomosing osteoid trabeculae and woven bone rimmed by osteoblasts
  • No invasion
  • No atypia
Differential diagnosis


Treatment
  • Curettage
  • En Bloc resection


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