Pathology Notes

Practice questions II answers, female genital tract Pathology of uterus © Jun Wang, MD, PhD 1. D. This patient presents with symptoms, signs and laboratory findings of acute inflammation. With the history of recent abortion, and tenderness on cervical movement, it is most likely acute endometritis , characterized by neutrophilic infiltrate of endometrium. Increased endometrial glands with budding and branching is seen in complex endometrial hyperplasia . Increase of irregular endometrial glands with glandular fusion and cytological atypia is seen in endometrioid endometrial adenocarcinoma . Increase of simple tubular endometrial glands is seen in simple endometrial hyperplasia . Normal proliferative endometrium would not cause symptoms of acute inflammation. 2. B. Presence of plasma cells in endometrium in an otherwise healthy patient is highly suggestive of chronic endometritis . Other conditions listed have changes of the number or morphology of endometrial glands, but

Practice questions II, female genital tract Pathology of uterus © Jun Wang, MD, PhD 1. A 25-year-old woman presents with lower abdominal pain associated with fever and chills for 1 day. She had a spontaneous abortion 3 days ago. Her past medical history is otherwise unremarkable. Per physical examination, she appears to be acutely ill with slightly tender lower abdomen. Speculum examination reveals small amount of purulent exudate pooled in the vaginal vault. Bimanual examination reveals extreme tenderness on cervical movement. No mass is noted. No other abnormality is noted. Laboratory test results include a white cell count at 17 x 109/L (normal 4.7-10.5 x 109/L) with 85% mature neutrophils and 5% bands. Toxic granulation is seen. No other abnormality is noted. What is the most likely finding in her endometrium? A. Increase of endometrial glands with budding and branching B. Increase of irregular endometrial glands with glandular fusion and cytological atypia C. In